The ability of thymidine to replace vitamin B12 as a growth factor for certain lactobacilli.
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چکیده
منابع مشابه
Effects of Vitamin B12 in Neonates and Young Infants
Vitamin B12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. Animal protein is the major dietary source of vitamin B12. Deficiency of vitamin B12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. Two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...
متن کاملThe effect of vitamin B12 on the leukopenia induced by radiation.
By ROBERT E. CARTER, M.D., ELIZABETH BUSCH, B.A., AND VERDA STRANG, B.A. V ITAMIN B12,1 2 a highly active liver principle containing cobalt3’ and an active growth-stimulating substance for Lactobacillus lactis,5 has been shown to be effective in the treatment of addisonian pernicious anemia and other macrocytic ‘#{176} Through the ability of thymidine to replace B12 as a growth factor for Lacto...
متن کاملPaper chromatography of vitamin B12 and related bacterial growth factors.
In a preliminary note (l), the present authors reported that Lactobacillus Eeichmannii 313 is capable of using six alternative factors for growth in vitamin Bn-deficient media. Two of these were found in vitamin Blz concentrates and presumably represent two forms of the vitamin. Hoffmann et al. (2) previously noted that crystalline antipernicious anemia factor (APA) (vitamin B1.J supports the g...
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Background: Alterations of systemic metabolic parameters are always present vitamins in cancer in addition radiotherapy may increases and complicates these disorders. The analysis of each biochemical metabolic alterations may give more understanding to biochemistry of malignancy and improving the degree of radiotherapy. The current study aimed to follow up the changes of folate, vitamin B12 a...
متن کاملRelationship between vitamin B12 oxidation product and sodium chloride toxicity for lactobacilli.
Beiler et al. (1951) reported that oxidation of vitamin B12 by hydrogen peroxide under strongly acid conditions resulted in the production of a colorless product which inhibited the vitamin B12 requiring microorganism, Lactobacillus leichmannii (ATCC 4797). Such inhibition was antagonized competitively by vitamin B12. Since we had observed that hydrogen peroxide itself competitively inhibited g...
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 175 1 شماره
صفحات -
تاریخ انتشار 1948